A Clinical Controlled Observation of Chinese Herbal Decoction (SMLJ01) for Type 1 Gastric Neuroendocrine Neoplasms

#2850

Introduction: Type 1 gastric neuroendocrine neoplasms (g-NENs) usually have good prognosis, however, most patients(pts) experience the recurrence after endoscopic resection.

Aim(s): To observe the clinical efficacy of Chinese herbal decoction SMLJ01 in the treatment of type 1 g-NENs.

Materials and methods: The study was conducted prospectively and retrospectively in the four centers of China from 2012 to 2019. Pts with type 1 g-NENs were non-randomly divided into the treatment group and control group after endoscopic treatment according to the wishes of the pts. The pts in the treatment group recieved oral administration of SMLJ01 and follow-up every 6-12 months, while the pts in the control group were follow-up alone. The analysis of recurrence-free survival (RFS) was performed by Kaplan-Meier method, and univariate analysis for risk factors was done by Cox-proportional hazards regression model after treatment for at least 6 months. The follow-up was until Oct 31, 2019.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Tan H

Authors: Chen Y, Han D, Zhu J, Chen J, Hu H,

Keywords: type 1 g-NENs, recurrence, Chinese herbs,