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Introduction: It has been demonstrated that mTOR inhibitors have potent anti-proliferative effects in a human Medullary Thyroid Carcinoma (MTC) cell line. We here explore the possible role of mTOR inhibitors, Everolimus and BEZ235 (which also inhibits the PI3K pathway) on the effects of Insulin-like Growth Factor-1 (IGF-1) in human MTC primary cultures.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Minoia m, Gentilin E, Rossi M, Tagliati F, Degli Uberti E,
Keywords: mTOR inhibitors, IGF-1, MTC,
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