Abstract Library

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ENETS Abstract Search

#2804 Claudin-18 Is a Sensitive and a Specific Marker for Gastric Neuroendocrine Tumors

Introduction: Antibody-based cancer therapies are emerging as promising therapeutics in oncology, including one in clinical trials that targets claudin-18, a protein expressed in normal gastric epithelium and some gastric adenocarcinoma. We currently have no markers for gastric well-differentiated neuroendocrine tumors (NETs).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Wong M, Huynh C, Kim S, Dhall D, Guindi M,

Keywords: claudin-18, anti-claudin 18, neuroendocrine tumor, neuroendocrine hyperplasia, autoimmune metaplastic atrophic gastritis,

#2199 Systematic Evaluation of the Immune Microenvironment of Neuroendocrine Tumors (NET)

Introduction: Immunotherapy is being explored in many tumour types with encouraging results, but its role in the management of NET is yet to be defined.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Vesely C

Authors: Vesely C, Childs A, Wong Y, Ogunbiyi O, Gander A,

Keywords: immunotherapy, neuroendocrine tumor, immune landscape, checkpoint molecules, t cells,

#2172 Well-Differentiated Neuroendocrine Lesions in Inflammatory Bowel Disease

Introduction: Whether inflammatory Bowel disease (IBD) increases the risk of developing neuroendocrine tumors (NETs) is not clear. NETs are rare in IBD, though one recent report suggests that NETs are 15 times more frequent in patients with Crohn’s disease. Besides NETs, which are discrete mass-forming lesions, microscopic neuroendocrine cell clusters or micronests (NEMs), difficult to measure, are sometimes observed in the lamina propria/muscularis mucosae of IBD patients.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Dhall D

Authors: Dhall D, Wong M, Larson B,

Keywords: Inflammatory bowel disease, neuroendocrine tumors, neuroendocrine micronests,

#2108 Molecular Characterization of Primary and Metastatic Pancreatic Neuroendocrine Tumors

Introduction: Pancreatic neuroendocrine tumours (PNETs) are a heterogeneous group of rare pancreatic neoplasms often diagnosed with distant metastases, which are associated with significantly poorer prognosis. Recurrent somatic mutations, chromosomal aberrations and gene expression signatures in PNETs have been described, but the clinical significance of these molecular changes is still poorly understood, and the clinical outcomes of PNET patients remain highly variable.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Yang K, Wong H, Shen Y, Colborne S, Kalloger S,

Keywords: pancreatic neuroendocrine tumor, metastasis, primary tumor, proteomics, transcriptomics,

#2024 Metachronous Primary Cancers in Neuroendocrine Tumor Patients

Introduction: Historically there has been an association between neuroendocrine tumours (NETs) and second primary cancers (Stronge et al 2014). However, this has not been well characterised.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Genus T

Authors: Genus T, Bouvier C, Wong K, Srirajaskanthan R, Rous B,

Keywords: Neuroendocrine cancer, second primary, metachronous,