Abstract Library

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ENETS Abstract Search

#3007 An mRNA-based Classifier Identifies PanNETs with Different Clinicopathological Characteristics

Introduction: Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms that varies from indolent to highly aggressive diseases. Previous studies have suggested alterations of ATRX/DAXX as biomarkers of dismal prognosis, yet inconclusive data (especially in the metastatic setting) prevent those biomarkers to be used as routine clinical tests.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Vicentini C, Barbi S, Bersani S, Rusev B, Lawlor R,

Keywords: PanNET, gene expression profile, ATRX/DAXX mutations, patients’ stratification.,

#2963 Intrinsic Gene Programs in Metastasis-like Primary Subtype Is Associated with Early Metastatic Evolution in Pancreatic Neuroendocrine Tumours

Introduction: Three molecular subtypes of pancreatic neuroendocrine tumours (PanNETs) have been described: insulinoma-like, intermediate and metastasis-like primary (MLP). The Latter is a non-functional tumours with highly metastatic potential. A mouse model of PanNET showed that MLP subtype has two different pathways of progression including stem/progenitor and epithelial-to-mesenchymal transition. However, the evolution of metastasis in patients requires further studies.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Sadanandam A

Authors: Sadanandam A, Lawlor R, Nyamundanda G, Ragulan C, Scarpa A,

Keywords: Pancreatic neuroendocrine tumors, metastasis, metastatic evolution, early metastasis, recurrence, prognosis, Patient tumours, cause and effect relationship, computational modeling, molecular subtypes, stages, metastatic potential,

#2086 miRNA Expression Defines Novel Subgroups of Small Intestinal Neuroendocrine Tumors

Introduction: Epigenetic dysregulation frequently occurs in cancers. Here we present the largest survival related miRNA profiling study to date of small intestinal neuroendocrine tumors (SI-NETs).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Arvidsson Y, Rehammar A, Bergström A, Andersson E, Altiparmak G,

Keywords: neuroendocrine tumor, small intestine, miRNA, profiling, cluster analysis, survival, miR-375, B-catenin,

#1370 68Ga-DOTATOC PET and Gene Expression Profile in Patients with Neuroendocrine Carcinomas

Introduction: Somatostatin receptor expression on both protein and gene expression levels were compared with in vivo 68Ga-DOTATOC PET/CT in patients with neuroendocrine carcinomas (NEC).

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Olsen I

Authors: Olsen I, Langer S, Federspiel B, Oxbøl J, Loft A,

Keywords: neuroendocrine carcinoma, gene expression, 68Ga-DOTATOC, IHC, SSTR2,

#654 Identification of Signaling Pathways Involved in Lung Carcinoid Progression Using Gene Expression Profiling

Introduction: Lung carcinoids are well-differentiated neuroendocrine tumors (NETs) usually associated with a favorable prognosis. Mechanisms underlying progression are poorly understood.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Swarts D, Van Neste L, Henfling M, Eijkenboom I, Van Velthuysen M,

Keywords: bronchial carcinoids, cDNA microarray, chromosomal passenger complex, immunohistochemistry, progression,