Abstract Library

#2982 Comprehensive Molecular Analysis Identifies Driver Mutations in Metastases of Sporadic Well-Differentiated Neuroendocrine Tumours of the Small Intestine

Introduction: Small intestinal neuroendocrine tumours (SI-NETs) represent a heterogenous group of tumours. The molecular mechanisms which contribute to progression of SI-NETs are poorly elucidated. They are considered to be molecularly distinct from neuroendocrine carcinomas (NECs), which share oncogenic pathways with adenocarcinomas.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Samsom K

Authors: Samsom K, van Veenendaal L, Roepman P, Kodach L, Steeghs N,

Keywords: whole genome sequencing, neuroendocrine tumour, small intestine, genetics,

#2977 Predicting Survival in Patients with a Neuroendocrine Tumor of the Small Intestine (SI-NET)

Introduction: SI-NET comprise the largest group of neuroendocrine tumors. Because of their heterogeneity, predicting survival has proven challenging. A nomogram (NG) to assess SI-NET disease specific survival (DSS) has been developed in 2010 by Modlin, et al. based on analysis of retrospective data from the Surveillance, Epidemiology and End Results (SEER) database.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Levy S, van Veenendaal L, Korse C, Verbeek W, Vriens M,

Keywords: SI-NET, Nomogram, Survival,

#2252 Safety and Efficacy of TAE and SIRT in NET Patients

Introduction: Transarterial embolization (TAE) and Selective Internal Radiation Therapy (SIRT) are used for treating patients with liver metastases of a neuroendocrine tumour (NET). However, the safety and effectiveness of TAE and SIRT have scarcely been compared.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Van Veenendaal L, Braat A, Meier M, Samsom K, Verbeek W,

Keywords: neuroendocrine tumor, liver metastases, therapy, radioembolization, transarterial embolization, safety, efficacy,

#1792 Treatment and Survival of 351 Patients Diagnosed with Merkel Cell Carcinoma in 2 Melanoma and Neuroendocrine Tumor Expert-Centers in the Netherlands

Introduction: Merkel cell carcinoma (MCC) is a rare and potentially aggressive neuroendocrine carcinoma of the skin. Because of its frequency, adequate data on treatment and survival are lacking.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: van Veenendaal L

Authors: Van Veenendaal L, Van Akkooi A, Verhoef C, Grünhagen D, Klop W,

Keywords: Merkel cell carcinoma, NEC,