Abstract Library

#3049 Organoid Models of Neuroendocrine Cell Growth and Tumorigenesis

Introduction: A paucity of in vitro and in vivo models has limited the study of Neuroendocrine neoplasms (NENs). Moreover, little is known about normal neuroendocrine (NE) cells and how they contribute to NEN formation.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Dayton T, Den Hartigh L, Levy S, van den Berg J, Kok N,

Keywords: Organoids, NENs, pulmonary neuroendocrine cells,

#2738 Patient-Derived Organoid Models of Human Neuroendocrine Carcinoma

Introduction: Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) is a poorly understood disease with limited treatment options. Due to its low incidence and wide tissue distribution few representative preclinical models are available

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Tesselaar M

Authors: Dijkstra K, van den Berg J, Weber F, van de Haar J, Velds A,

Keywords: organoids, gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC), disease modeling, pre-clinical models,

#2181 Using Adult Stem-Cell Derived Organoids to Model Neuroendocrine Tumor Growth

Introduction: Neuroendocrine tumors (NETs) are a genetically diverse set of rare tumors, which have limited treatment options. The development of more effective therapies for NETs has been limited in part by the absence of in vitro and in vivo models that accurately represent the heterogeneity of these tumors.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Dayton T

Authors: Dayton T, Beumer J, Den Hartigh L, Leewaarde R, Van den Berg J,

Keywords: Organoids, neuroendocrine tumors,