Abstract Library
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ENETS Abstract Search
#2896 Comparative Genomic Analysis of High Grade Neuroendocrine Neoplasms across Diverse Organs
Introduction: Grade 3 neuroendocrine neoplasms (G3 NENs), if poorly differentiated, have a median survival of 10-19 months. Little is known regarding biologic differences between G3 NENs from different primary sites, most commonly GI and lung.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Sun T
Authors: Sun T, Van Hummelen P, Martin B, Xia C, Zhao L,
Keywords: grade 3, high grade, neuroendocrine carcinoma, whole exome sequencing, rna-seq, transcriptomics, copy number analysis, sequencing, genomics, poorly differentiated,
Introduction: Gastric mixed adenoneuroendocrine carcinomas (g-MANECs) are rare neoplasms consisting of adenocarcinoma and neuroendocrine neoplastic components. G-MANECs show more malignant characteristics than gastric adenocarcinomas, while molecular mechanisms underlying the co-existence of the two components remains unknown.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Yan S, Chen X, Zhang R, Song L, Yin F,
Keywords: whole exome sequencing, mixed adenoneuroendocrine carcinoma, Stomach, Evolution,
Introduction: While the genomic and transcriptomic landscape of low proliferating PanNET have been well studied, pathways driving aggressive WD PanNET are still unclear.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Cros J, Soukeur M, Raffenne J, Bernard V, Scoazec J,
Keywords: Exome sequencing, Pancreatic NET, G3 NET,
#1461 Whole Exome Sequencing of Three Families with Small Intestine Neuroendocrine Tumors
Introduction: Small intestine neuroendocrine tumors (siNETs) are the most prevalent small intestine neoplasms. However, familial siNETs are rarely described.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author:
Authors: Beyens M, Vandamme T, Goepfert A, Van Camp G, Hofland L,
Keywords: Familial siNET, whole exome, candidate gene,
Introduction: Treatment with the mTOR-inhibitor everolimus improves progression-free survival in advanced pancreatic neuroendocrine tumors (PNETs). However, adaptive resistance to mTOR inhibition is described.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Vandamme T
Authors: Vandamme T, Op de Beeck K, Beyens M, Mortier G, Pauwels P,
Keywords: everolimus,