Abstract Library

#2885 Ectopic Neuroendocrine Carcinoma: An Occult Source of ACTH

Introduction: About 250 cases of ectopic ACTH-producing neuroendocrine carcinoma (ACTH-NEC) have been reported; however metastatic ACTH-NEC of unknown primary is very rare. Usually are characterized by having a large cell, small cell, poorly differentiated or anaplastic cell, and Ki-67 index between 40-90%.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Alvaréz Figueroa J, Aguirre Matallana D, Cañón Solano D,

Keywords: Ectopic ACTH production, Cushing’s syndrome, Neuroendocrine carcinoma, Paraneoplastic Cushing syndrome, Ectopic Cushing´s syndrome,

#2773 Impact on Outcome in Patients (pts) with Advanced Neuroendocrine Neoplasms (NENs) Included in Prospective Clinical Trials (CT)

Introduction: Access to CT offers cancer pts the opportunity to receive new treatments and better monitoring of efficacy and toxicity. The increase of systemic therapy options in advanced NENs has relegated the inclusion of pts in CT to later lines of treatment as suggested in most guidelines.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Hernando J

Authors: Hernando J, Vukovic P, Garcia-Alvarez A, Díaz N, Cameselle-Garcia S,

Keywords: Clinical Trial, Neuroendocrine Neoplasms, Overall Survival,

#2749 Impact of Next-Generation Sequencing Analyses on Treatment Management of Patients with Advanced Neuroendocrine Neoplasms

Introduction: Molecular genomic analyses are widely used in oncology but experience in advanced neuroendocrine neoplasms (NENs) is still limited.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Garcia Alvarez A

Authors: Garcia-Alvarez A, Hernando J, Vivancos A, Landolfi S, Casteras A,

Keywords: NGS, BRAF, RET,

#966 Evaluation of Lysyl Oxidase-Like-2 (LOXL2) Expression by Immunohistochemistry (IHC) in Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET): A Retrospective Analysis and Comparison with PTEN

Introduction: A better understanding of the relationship between the stroma and the cancer cells of this group of malignancies remains a challenge. LOXL2 is an enzyme that contributes to the synthesis and stabilization of the cellular matrix and plays a role in angiogenesis.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Barriuso J

Authors: Barriuso J, Bernal E, Pastrian L, Alvárez-Escolá C, Martinez J,

Keywords: LOXL2, GEP-NET,

#641 Metastatic Gastroenteropancreatic Neuroendocrine Tumors (GEP NETs) Management in a Spanish University Hospital

Introduction: GEP-NETs are malignant entities poorly understood still, deserving important attention for a better management of the disease.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Solís M

Authors: Solís M, Fonseca P, Faez L, Álvarez C, Pérez Q,

Keywords: metastatic, GEP-NETs, clinical practice, markers, surgery, chemotherapy,