A Rare Case of Paraneoplastic Hypercalcemia Secondary to a Neuroendocrine Pancreatic Tumour (pNET).

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Introduction: Paraneoplastic hypercalcemia (HC) is a well-described affection in literature. It can relay on several mechanisms among with bone osteolysis, Parathormone (PTH) related peptide (rp) production, primary hyperparathyroidism, and Calcitriol (CT) secretion. CT secretion-mediated HC is more frequently observed among lymphomas and has only been once reported in pNET.

Aim(s): Based on this case report, we reviewed paraneoplastic HC in pNET and its mechanisms.

Materials and methods: We present here the case of a 55 year old man whom arrived at the emergency room with fever associated with an major inflammatory syndrome and HC (3.05mmol/l, 2.15-2.5).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Belaïd A, Dhenin A, Jopart P, Seront E, Grandjean M,

Keywords: paraneoplastic hypercalcemia, pancreatic neuroendocrine tumor, calcitriol,