Clinical Characteristics and Treatment Outcome of Advanced G3 Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)- A Retrospective Analysis

#1781

Introduction: Advanced poorly differentiated GEP-NEC are uncommon neoplasms and treated mainly with platinum-based chemotherapy associated with etoposide.

Aim(s): To assess the clinical characteristics and various predicting factors.

Materials and methods: 10 patients with advanced GEP-NEC, with ki 76 index above 20% treated in our center in the last 8 years were reviewed. Data about site of the primary tumor, presence of metastasis, alkaline phosphatase (ALKP) value and neutrophil/lymphocytes ratio and survival were collected.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Croitoru A

Authors: Grigorescu R, Stanel I, Gramaticu I, Dinu I, Buica F,

Keywords: GEP-NEC, chemotherapy, prognostic factors,