Development of Effective Prophylaxis Against Intraoperative Carcinoid Crisis

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Introduction: Patients with foregut and midgut neuroendocrine tumors (NETs) can experience life-threatening carcinoid crises during anesthesia. The prophylactic use of a pre-, intra- and post-operative high dose continuous octreotide infusion was evaluated for its ability to prevent carcinoid crises during cytoreductive surgeries.

Aim(s): To develop an effective anesthesia protocol to prevent intraoperative carcinoid crises

Materials and methods: Anesthesia and surgical records of 188 patients who underwent a total of 228 cytoreductive surgeries for stage IV, small bowel NETs were reviewed. All patients received a 500 microgram/hour infusion of octreotide pre-, intra- and post-operatively. Patients that experienced intraoperative hyper- or hypotension, profound tachycardia, or a “crisis” according to the operative note were also reviewed.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Woltering E

Authors: Woltering E, Diebold A, Stevens M, Wang Y, Boudreaux J,

Keywords: carcinoid crisis,