Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH): Characterisation of Prevalence and Prognosis in the Pulmonary Carcinoid Population


Introduction: DIPNECH is considered a rare condition and the natural history is poorly described. It is thought to give rise to pulmonary carcinoids (PCs) (>5mm) or tumourlets (≤5mm).

Aim(s): We aimed to assess the prevalence and characteristics of DIPNECH in the PC population and to investigate predictors of progression-free (PFS) and overall survival (OS).

Materials and methods: We identified patients with PCs and histologically-proven DIPNECH and/or high suspicion of DIPNECH on imaging. Relationship between baseline characteristics and PFS and OS was analysed using the Kaplan-Meier method and curves were compared using the logrank test.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Hayes A

Authors: Hayes A, Banks J, Shah H, Luong T, Navalkissoor S,

Keywords: dipnech, diffuse idiopathic neuroendocrine cell hyperplasia, tumourlet, carcinoid, neuroendocrine tumor, multiple pulmonary nodules,

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