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Effects of Debulking Surgery, Transarterial Embolisation (TAE) and Transarterial Chemoembolisation (TACE) on Quality of Life in Patients with Metastatic Ileal and Pancreatic Neuroendocrine Tumours (NETs)


Introduction: Debulking surgery, TAE and TACE procedures are undertaken in patients with metastatic NETs. Reducing the physical burden of disease may prolong survival and can improve the quality of life of patients. However, there is only limited quality of life data available after surgery despite the fact that is has been used routinely for many years.

Aim(s): To evaluate the impact of debulking surgery and liver directed therapy (TACE, TAE) in metastatic NETs, on quality of life (QoL). Additionally, to see how long it takes for quality of life to improve after treatment.

Materials and methods: A prospective longitudinal cohort study, from October 2017, was undertaken at University Hospital Southampton. Patients who were due to receive debulking surgery, TAE or TACE were included. EORTC QLQ-C30, EORTC QLQ-GINET21 and EQ-5D were used pre-op, post-op and at 3 monthly intervals up to 18 months. Participants were a consecutive cohort of patients who were approached and willing to give consent.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Sinclair A, Tanno L, Jarvis E, Ramsey E, Naheed S,

Keywords: Quality of Life, Debulking Surgery, TAE, TACE, Metastatic, NETs,

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