Efficacy of Topotecan in Pretreated Metastatic Neuroendocrine Carcinoma
#1095
Introduction: Therapeutic options for metastatic poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC) after prior platinum-based chemotherapy are limited. Topotecan is an approved second line chemotherapy for small cell lung cancer (SCLC) which is often considered to show a biological behavior similar to NEC.
Aim(s): To analyze the efficacy of topotecan in pretreated metastatic NEC patients.
Materials and methods: We performed an updated retrospective analysis of all patients treated with topotecan for metastatic NEC who presented at our center between January 2005 and December 2013.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Apostolidis L
Authors: Apostolidis L, Jäger D, Winkler E,
Keywords: neuroendocrine carcinoma, chemotherapy, topotecan,
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