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Endometrial Small Cell Neuroendocrine Carcinoma: Case Report and Literature Review


Introduction: Endometrial small-cell neuroendocrine carcinoma (ESCNEC) is extremely rare. It is characterized by early regional and systemic spread leading to rapid development of lymph nodes, pelvic and extrapelvic metastasis and compromising the outcome.

Aim(s): we report the case of ESCNEC confirmed by pathological and immunohistochemistry studies. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis, and discuss therapeutic options and prognosis.

Materials and methods: A 61-year-old women patient with good ECOG PS 1, suffering postmenopausal bleeding presented to hospital with. No radiological explorations have been carried out. She underwent surgery with radical hysterectomy plus bilateral salpingooophorectomy, pelvic and para-aortic lymphadenectomy and peritoneal cytology.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Aris H, Ghomari S,

Keywords: endometrial small cell neuroendocrine carcinoma, surgery, adjuvant chemotherapy, brachytherapy,

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