Insulinomas in Children

#403

Introduction: Insulinomas are extremely rare tumors in children and an uncommon first manifestation of MEN1 syndrome. Insulinomas are usually benign tumors with only a few reports of malignant cases in children.

Aim(s): To investigate the morphological and genetic characteristics of Russian children with primary insulinomas.

Materials and methods: Insulinoma was diagnosed biochemically and by imaging and was verified histopathologically. Sequencing of the MEN1 gene was performed and families of the mutation carriers were studied. Follow-up included screening for signs of MEN1 and metastases in case of malignant tumors.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Melikian M, Gurevich L, Averyanova Y, Friis-Hansen L, Christesen H,

Keywords: MEN-1,