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Interim Analysis of Prospective Evaluation of the Management of Sporadic Nonfunctioning Asymptomatic Pancreatic Neuroendocrine Neoplasms ≤ 2 cm (ASPEN Study)


Introduction: Guidelines recommend a watchful strategy for small, incidental, nonfunctioning pancreatic neuroendocrine neoplasms (NF-PanNEN).

Aim(s): To evaluate the management of asymptomatic NF-PanNEN ≤ 2 cm.

Materials and methods: Prospective multicenter cohort study supported by European Neuroendocrine Tumor Society (ENETS) (NCT03084770). Overall, 387 patients with sporadic asymptomatic NF-PanNEN ≤ 2 cm were enrolled by 40 Institutions worldwide (August 2017-November 2019). Data for an interim analysis were available for 354 patients. Patients underwent active surveillance (AS) or surgical resection (SR) according to referral physician choice.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Partelli S

Authors: Partelli S, Zerbi A, Massironi S, Jin-Young J, Landoni L,

Keywords: small neuroendocrine pancreatic tumors, surveillance, surgery, follow-up,

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