Natural Course and Survival of Thymic and Bronchopulmonary Neuroendocrine Tumors are Different for Male and Female MEN-1 Patients
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Introduction: The course of thymic- and bronchopulmonary neuroendocrine tumors (Th- and Bp-NET) in MEN-1 patients is still unclear.
Aim(s): To assess the prevalence, natural course and survival Th- and Bp-NET in an unselected MEN-1 population with long-term follow-up.
Materials and methods: A longitudinal study was performed using the Dutch national MEN-1 database, including 90% of the Dutch MEN-1 population. Patients >16 years, under the care of the Dutch University Medical Centers (1990-2010) (n=294) were included. Prevalence and survival of Th- and BpNET was assessed. Linear mixed models analysis was applied with gender, genotype and baseline tumor size as possible effect modifiers.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: De Laat J, Pieterman C, Twisk J, Hermus A, Dekkers O,
Keywords: MEN-1, lung NET, thymic NET, natural course, survival,
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