Prospective Validation of Prognostic Score in High-Grade Gastrointestinal Neuroendocrine Carcinomas (GI-NECs)

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Introduction: Prognostic markers for risk-stratification of GI-NECs are lacking.

Aim(s): We aimed to validate our prognostic score for GI-NECs (liver metastases, alkaline phosphatase, lactate dehydrogenase, ECOG performance status (PS) and Ki67; Lamarca et al, ASCO 2015).

Materials and methods: We prospectively identified all consecutive patients (pts) diagnosed with GI-NECs seen at The Christie (July’14-Nov’15). Our previously designed score was applied. Cox regression and Kaplan Meier were used for survival analysis.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Lamarca A

Authors: Lamarca A, Barriuso J, McNamara M, Hubner R, Valle J,

Keywords: NEC, score, overall survival, high grade, prognostic,