Second Primary Malignancies in Patients with Neuroendocrine Tumors

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Introduction: Numerous studies have demonstrated an elevated incidence of second primary malignancies (SPM) in patients with neuroendocrine tumours (NET).

Aim(s): To review our institutional experience of SPM in NET patients.

Materials and methods: Individual patient notes were obtained: data regarding gender, age, date and type of diagnoses were extracted. Patients with any tumour pre-disposition syndrome were excluded. SPM were classed as previous, synchronous, or metachronous relative to NET diagnosis. A person-year methodology was used to compare the observed frequencies of SPM against expected values generated using age- and sex-specific incidence tables, with standardised incidence ratios (SIRs) and 95% confidence intervals (CI) calculated.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Clift A, Drymousis P, Al-Nahhas A, Wasan H, Martin J,

Keywords: neuroendocrine, neoplasm, second, cancers,