Should Surgery Be Conducted for Small Nonfunctioning Pancreatic Neuroendocrine Tumors: A Systemic Review

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Introduction: Researches showed controversial results regarding whether surgery should be conducted for nonfunctioning pancreatic neuroendocrine tumors (PNETS) smaller than 2 cm. Both the ENETS and NCCN guidelines recommended observation for selected cases, while none of them pointed out which cases should be chosen.

Aim(s): To find out whether PNETS smaller than 2 cm need surgery and which subgroup would benefit the most from surgery.

Materials and methods: MEDLINE, EMBASE and CENTRAL were searched until 2016/08/30, with primary outcome being overall survival, and secondary outcome being progression free survival, disease specific survival and disease recurrence/progression.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Zhao H

Authors: Guo J, Zhao J, Bi X, Li Z, Huang Z,

Keywords: PNETS, 2 cm, surgery,