Introduction: Carcinoid syndrome (CS) occurs when metastatic carcinoid tumors secrete large amounts of serotonin (5-HT) and other bioactive substances into systemic circulation, causing a variety of symptoms, including GI symptoms such as profound diarrhea. Reduction in 5-HT production by the tumor would be expected to improve symptoms in patients with CS.
Conference: 7th Annual ENETS Conference (2010)
Presenting Author: Jay L Mitchell
, TPH inhibitor
, tryptophan hydroxylase
, clinical trial
, serotonin synthesis inhibitor
, irritable bowel syndrome
Introduction: Gastroenteropancreatic neuroendocrine tumors have been seldom described in association with neurofibromatosis type-1, whereas an association with neurofibromatosis type-2 (NF2) has never been reported.
Conference: 10th Annual ENETS Conference (2013)
Category: Epidemiology/Natural history/Prognosis - Descriptive epidemiology
Presenting Author: Dr Roberta E Rossi