Abstract library

5 results for "Lupp".
#1060 Fifty-Three Year-Old-Male with a Symptomatic Ileocecal Carcinoid: An Individual Follow-Up of 14 Yrs with 5 Different Anti-Proliferative Therapies
Introduction: Only limited reports exist about sequence of different anti-tumor therapies in patients with neuroendocrine tumors (NETs) after primary surgery.
Conference: 12th Annual ENETS Conference (2015)
Category: Clinical cases/reports
Presenting Author: MD Patrizia Kump
#22 A Case Illustrative of Phenotypic Heterogeneity and Challenges in the Management of Paraganglioma
Introduction: Paragangliomas (PGLs) are extra-adrenal, usually benign, highly vascularized tumors that originate from neural-crest-derived chromaffin cells. These tumors are subdivided as either sympathetic or parasympathetic, depending on their location and catecholamine production. Sympathetic PGLs are situated along the abdominal sympathetic trunk and usually produce catecholamines, whereas parasympathetic PGLs are located in the head and neck, and these usually do not produce catecholamines. PGLs may present as sporadic or inherited tumor syndrome, including MEN 2, with RET germline mutations, von Hippel-Lindau (VHL) disease due to germline mutations in VHL gene, and pheochromocytoma-PGL syndrome. The latter is frequently a hereditary condition and is caused by germline mutations in the SDHB, SDHC, or SDHC genes. Patients with familial PGLs may present at a younger age, often as multifocal tumors, with an increased risk of recurrence and a higher frequency of malignancy in those with SDHB mutations. SDH mutations induce angiogenesis and tumorogenesis through the inhibition of hypoxia-inducible factors (HIF)-propyl hyroxylase. A younger age at onset, malignancy, and a positive family history are clinical parameters of high specificity, but low sensitivity for diagnosis. Genetic analysis for mutations in SDH genes for the patient and family members, and surveillance for the affected patient and family members, are necessary where there are no clear clinical or family indicators for the syndrome. We present a case of a large abdominal malignant PGL in a 20-year-old pt. that went on without clinical detection for at least three years.
Conference: 7th Annual ENETS Conference (2010)
Category: Clinical
Presenting Author: Dr Mohammed Ahmed
#23 Developing a customized database for NET in a developing country
Introduction: The establishment of a neuroendocrine registry is extremely hard in developing countries. Many patients miss follow-up after surgical procedures and many die in different hospitals with a distinct national security health system number. As in any developing country, Brazil has a large movement of people to urban areas, making the tracking of former addresses impossible for patients who were treated some years prior. Therefore, it is more feasible to evaluate a demographic distribution of neuroendocrine tumors by topography or histological subtype, but the analysis of clinical events, such as progression-free survival, disease-free survival, time to progression or overall survival, is compromised.
Conference: 7th Annual ENETS Conference (2010)
Category: Clinical
Presenting Author: PhD Bernardo Garicochea
#286 Aberrant Expression of FSH Receptor in Pancreatic Neuroendocrine Tumors
Introduction: FSH receptor (FSHR) expression is restricted to gonads. FSHR plays an important role in regulation of ovarian angiogenesis. Recently, FHSR expression has been shown in blood vessels of various tumors.
Conference: 8th Annual ENETS Conference (2011)
Category: Clinical
Presenting Author: Prof Fausto Bogazzi
Authors: Russo D, Locci M T, Raggi F, Chifenti B, ...
#1061 Transcatheter Arterial Chemoembolization for Unresectable Metastatic Hepatic Lesions of Pancreatic Neuroendocrine Tumors
Introduction: The blood supply of metastatic hepatic neuroendocrine tumors is mainly supplied by hepatic arteries. For unresectable metastatic NETs, selective embolisation of the hepatic arteries may be therapeutic.
Conference: 12th Annual ENETS Conference (2015)
Category: Medical treatment - Others
Presenting Author: Bao Xin
Authors: Xin B, Lou W, Ji Y, Liu L X, ...
Keywords: pnet, hepatic lesion, tace