Abstract library

109 results for "ihc".
#2981 The Distance from Pathology to Molecular Imaging: SSTR Expression Comparison in 100 Gastroenteropancreatic Neuroendocrine Neoplasms
Introduction: Somatostatin receptor (SSTR) overexpression is a unique feature of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), which establish the basis for both diagnosis and therapy. SSTR status can be evaluated by immunohistochemical staining (IHC) and 68Ga-DOTATATE PET/CT.
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Pathology - grading, staging
Presenting Author: Jiangyuan Yu
Authors: Yu J, Cao F, Yang Z, Sun Y
Keywords: GEP-NEN, SSTR, PET/CT, IHC
#1807 Adherence to WHO2010 Guideline for Diagnosis of Neuroendocrine Carcinoma and Prognostic Significance
Introduction: Neuroendocrine carcinoma’s (NEC) are diagnosed by a combination of immunohistochemistry (IHC) and morphology according to the 2010 WHO guidelines.
Conference: 14th Annual ENETS conference 2017 (2017)
Category: Pathology, grading, staging
Presenting Author: Wouter Zandee
#644 Diffuse Expression of Osteopontin, Endostatin and Angiopoietin 1 in Neuroendocrine Neoplasm Tissues
Introduction: Recent data show a characteristic pattern of selected angiogenic factors of plasma levels: endostatin(END), osteopontin(OPN), angiopoietin 1 & 2 (Ang-1&2) in patients with neuroendocrine neoplasm (NEN) in comparison to healthy controls.
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: Basic Science - mTOR and other pathways, signalling, receptors
Presenting Author: Professor Gabriela Mełen-Mucha
#833 The Chemokine Receptor CXCR4 – Differential Expression in Bronchopulmonary Neuroendocrine Neoplasms
Introduction: The CXCR4 is a plasma membrane chemokine receptor, which is involved in organogenesis, hematopoiesis and inflammation. Additionally, an over-expression is described for many neoplastic tissues. Here, an involvement in tumor progression, metastasis, adaptation to hypoxia and in stem cell survival is postulated.
Conference: 11th Annual ENETS Conference 2014 (2014)
Category: Biomarkers
Presenting Author: Christiane Anne Reimann
#2812 SILVELUL Project: Development of an New Potential Predictive Immunohistochemical Score (SPI) in Patients (pts) with Pancreatic Neuroendocrine Tumors (PanNET) Treated with CAPTEM or Everolimus
Introduction: Previously our group showed the potential use of a score based on MGMT, NDRG-1 and PHLDA-3 immunohistochemistry (IHC) expression as predictor of outcome in operated PanNET (Viúdez et al. Oncotarget 2016).
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Biomarkers
Presenting Author: MD PhD Antonio Viudez
#417 CK19 Expression in A?TH-Producing Extrapituitary Neuroendocrine Neoplasms is a Negative Prognostic Factor
Introduction: Defining localization and potential ?CTH-producing extrapituitary neuroendocrine neoplasms (ACTH-epNEN) is important for clinical practice.
Conference: 9th Annual ENETS Conference (2012)
Category: Basic
Presenting Author: I Voronkova
#480 Immunohistochemical (IHC) Overexpression of Succinate Dehydrogenase (SDHB) as Prognostic Factor in Sporadic Pheochromocytomas/Paragangliomas (P/P)
Introduction: Recently, gene mutations (SDH complex) involved in the pathogenesis of familial P/P have been discovered. These mutations are often associated with SDHB activity loss and activation of hypoxia signals.
Conference: 9th Annual ENETS Conference (2012)
Category: Basic
Presenting Author: MD Sara Pusceddu
#171 Transcription Factor Signature in Pancreatic and Duodenal Neuroendocrine Neoplasms
Introduction: We recently identified ISL1 as a marker for pancreatic neuroendocrine neoplasms (P-NENs). ISL1 as well as PDX1, CDX2 and NGN3 are transcription factors (TF) involved in pancreato-duodenal development.
Conference: 8th Annual ENETS Conference (2011)
Category: Basic
Presenting Author: Gratiana Hermann
#384 A Pilot Study on the Immunohistochemical Expression of Chromogranin and/or Synaptophysin in Moderate to Poorly Differentiated Gastroenteropancreatic Carcinomas
Introduction: Recent advances in specific treatment for neuroendocrine tumors (NETs) prompted us to reinvestigate the old phenomenon of neuroendocrine differentiation in carcinomas of the GI tract which has previously been shown to carry no prognostic significance.
Conference: 9th Annual ENETS Conference (2012)
Category: Clinical
Presenting Author: Dr tony W Shek
Authors: Shek T W, Lam W Y, Yao H, Tang V, ...
Keywords: NET, IHC
#646 Immunohistochemical (IHC) and Cytogenetic Approach for Improving Diagnosis and Therapy of Ewing Sarcoma (ES)/pPNET Arising in the Ileocecal Region
Introduction: ES/pPNET primary to the ileocecal region (IpPNET) have been rarely reported on and show close similarities in histology and clinical presentation with small round blue cell tumors. The EWS gene is fused to four members of the ETS family.
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: Pathology, grading, staging
Presenting Author: Md, PhD Massimo Milione
Keywords: EWS, pPnet, FEV