Abstract library

180 results for "mesenteric vascular infiltration".
#2693 The Distinctive Character of Micro-Vasculature and Immune Cell Infiltration in Cystic Pancreatic Neuroendocrine Tumors
Introduction: Hypervascularity is main character of pancreatic neuroendocrine tumors (PanNETs), cystic PanNET (CPanNET) are unique type of PanNETs for which the microenvironment remains unknown.
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Biomarkers
Presenting Author: Heli Gao
Authors: Gao H
#2288 Predicting Resectability of Primary Tumor and Mesenteric Lumps in Patients with Small Intestine Neuroendocrine Tumors
Introduction: Vascular infiltration and mesenteric fibrosis may jeopardize resection of primary tumor (PT) and mesenteric metastatic lumps (MLs) in small-intestine neuroendocrine tumors (SI-NETs).
Conference: 15th Annual ENETS conference 2018 (2018)
Category: Surgical treatment and Ablative Therapies
Presenting Author: MD Alessandra Nella Piccioli
#2999 Aberrant Tryptophan Metabolism in Stromal Cells Is Associated with Mesenteric Fibrosis in Small Intestinal Neuroendocrine Tumours
Introduction: Increased levels of serotonin secretion are associated with mesenteric fibrosis (MF) in small intestinal neuroendocrine tumors (SI-NETs). However, only a proportion of patients with increased serotonin production will develop mesenteric fibrosis.
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Basic Science - Genetics, epigenetics, miRNAs, Omics
Presenting Author: Drs. Anela Blazevic
#2995 Prediction of Symptomatic Mesenteric Mass in Patients with Small Intestinal Neuroendocrine Tumors Using a CT Radiomics Approach
Introduction: A mesenteric mass surrounded by fibrosis is a hallmark feature of small intestinal neuroendocrine tumors (SI-NETs) that can induce severe abdominal complications. To improve clinical outcome, there is a need for personalized treatment strategies based on accurate prediction of development of abdominal complications.
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Imaging and Interventions (radiology, endoscopy)
Presenting Author: Drs. Anela Blazevic
#22 A Case Illustrative of Phenotypic Heterogeneity and Challenges in the Management of Paraganglioma
Introduction: Paragangliomas (PGLs) are extra-adrenal, usually benign, highly vascularized tumors that originate from neural-crest-derived chromaffin cells. These tumors are subdivided as either sympathetic or parasympathetic, depending on their location and catecholamine production. Sympathetic PGLs are situated along the abdominal sympathetic trunk and usually produce catecholamines, whereas parasympathetic PGLs are located in the head and neck, and these usually do not produce catecholamines. PGLs may present as sporadic or inherited tumor syndrome, including MEN 2, with RET germline mutations, von Hippel-Lindau (VHL) disease due to germline mutations in VHL gene, and pheochromocytoma-PGL syndrome. The latter is frequently a hereditary condition and is caused by germline mutations in the SDHB, SDHC, or SDHC genes. Patients with familial PGLs may present at a younger age, often as multifocal tumors, with an increased risk of recurrence and a higher frequency of malignancy in those with SDHB mutations. SDH mutations induce angiogenesis and tumorogenesis through the inhibition of hypoxia-inducible factors (HIF)-propyl hyroxylase. A younger age at onset, malignancy, and a positive family history are clinical parameters of high specificity, but low sensitivity for diagnosis. Genetic analysis for mutations in SDH genes for the patient and family members, and surveillance for the affected patient and family members, are necessary where there are no clear clinical or family indicators for the syndrome. We present a case of a large abdominal malignant PGL in a 20-year-old pt. that went on without clinical detection for at least three years.
Conference: 7th Annual ENETS Conference (2010)
Category: Clinical
Presenting Author: Dr Mohammed Ahmed
#168 Neuroendocrine Tumors - Imaging Abdominal Complications
Introduction: Neuroendocrine tumors mostly arise from the gastrointestinal tract and pancreas but also from bronchopulmonary or any other organ. Abdominal complications are usually associated with the primary GI tract tumor.
Conference: 8th Annual ENETS Conference (2011)
Category: Basic
Presenting Author: MD Joana Ip
Authors: Ip J, Claro I, Duarte I, ...
#884 Simultanenous Duplicate Malignant Disease-Adenocarcinoma of the Colon and Disseminated Neuroendocrine Tumor
Introduction: Fifty-nine-year old man, under examination due to weight loss, enterorrhagia, general abdominal discomfort. Endoscopy detected tumorous infiltration 20 cm from the anus, bleeding. Histology: adenocarcinoma. CT abdomen detected liver lesion. The lesion was hypervascularized, and the CT picture was atypical for metastatic adenocarcinoma. CT chest: tumor lesion in the left lower segment, metastatic LN in mediastinum. According to the CT, the picture is atypical for metastases.
Conference: 11th Annual ENETS Conference 2014 (2014)
Category: Clinical cases/reports
Presenting Author: M.D. Lenka Ostrizkova
#1006 The Use of Endoluminal Stents to Overcome Vascular Obstruction Arising from Mesenteric and Retroperitoneal Neuroendocrine Metastases
Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP-NET) often metastasise to lymph nodes. Nodal metastases from neuroendocrine tumors in the distal small intestine commonly (>50%) develop in the mesentery and are often centred at the mesenteric root surrounding the major vessels supplying the bowel. Compression of these vessels, by the nodes or associated fibrosis, can lead to severe symptoms such as pain (secondary to bowel ischaemia ), ascites (from superior mesenteric vein obstruction) and bowel perforation. In view of the often indolent nature of GEP-NET, symptoms from lymph node masses can persist for years, causing significant morbidity and early mortality.
Conference: 11th Annual ENETS Conference 2014 (2014)
Category: Clinical cases/reports
Presenting Author: Dr Alan Anthoney
Authors: Anthoney A, Patel J, Kamposioras K, ...
#1053 Pancreatic Neuroendocrine Tumor and Ileal Carcinoid in Acromegaly. Pluriglandular Association in Non-MEN 1 Patient: A Case Report.
Introduction: Pluriglandolar endocrine disease in patients without familial inherited disease (non-MEN 1) are very rare. Primary Pancreatic Neuroendocrine Tumors (pNET) and ileal carcinoid tumors have different embryologic origin (foregut and midgut respectively).
Conference: 12th Annual ENETS Conference 2015 (2015)
Category: Clinical cases/reports
Presenting Author: Doctor Valbona Lico
#1113 A Novel Approach for a Metastatic Gut-Derived Neuroendocrine Tumour: Simultaenous Intestinal and Vascularised Sentinel Forearm Flap Transplantation
Introduction: Non-resectable tumours involving the mesenteric root are an indication for intestinal and multivisceral transplantation (MVT). Vascularised sentinel forearm flaps (VSFF) offer possibilities for monitoring graft rejection and tailoring immunosuppression (IS) regimens.
Conference: 12th Annual ENETS Conference 2015 (2015)
Category: Clinical cases/reports
Presenting Author: Ashley Clift
Authors: Clift A, Giele H, Vrakas G, Reddy S, ...