Introduction: For many cancer entities, inflammation has been shown to play an important role in pathogenesis and progression.
Aim(s): To investigate the association between preoperative plasma levels of C-reactive protein (CRP) and overall survival (OS) in patients with pancreatic neuroendocrine neoplasia (pNEN).
Materials and methods: A prospective database of patients with pNENs was retrospectively analysed with focus on initial preoperative CRP blood levels (<5 mg/l vs ≥5 mg/l). Among 149 patients with sporadic pNEN, Kaplan-Meier method and Cox regression were used to evaluate the relationship between CRP and clinical outcome, defining overall survival as primary endpoint. Possible association between CRP-levels and the other prognostic factors was investigated via crosstabulation and Pearson-χ2-test.
Conference: 13th Annual ENETS conference 2016 (2016)
Presenting Author: Prof. Dr. Volker Fendrich
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