Accidental Injection of Unlabeled Lu-177 Caused Catastrophic Consequences in Patients with Neuroendocrine Tumor

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Introduction: Since Lu-177 DOTATATE treatment is not approved in South Korea, patients with neuroendocrine tumors were sent to Germany and Malaysia for the treatment.

Aim(s): We report a radiation accident due to free Lu-177 injection to patients.

Materials and methods: In 12 Nov. 2018, 7.7~8.1 GBq of unlabeled Lu-177 were accidentally injected to five patients (1 male and 4 female) with neuroendocrine tumor from South Korea at a hospital in Malaysia. Radiation dose to patients was estimated using biokinetic model of lutetium based on the animal experiments in ICRP Publication 30.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Kang K, Song Y, Kwon T, Ha W, Jin Y,

Keywords: radiation accident, PRRT, neuroendocrine tumor,