Added Prognostic Value of Molecular Imaging Biomarkers over Proliferation Index in Typical Lung Carcinoid: An FDG PET and SSTR Imaging Study

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Introduction: Typical lung carcinoids(TCs)are rare tumors with good,although heterogeneous,prognosis.

Aim(s): To evaluate the prognostic meaning of FDG PET and somatostatin receptor(SSTR)imaging biomarkers,in patients with TCs,and their relationship with Ki67.

Materials and methods: We reviewed 68patients with histological diagnosis of lungTCs,with Ki67 measured,FDG PET and/or SSTR SPECT with 111In-pentetreotide at staging and follow-up of at least 1 year,to determine overall survival(OS).We measured SSTR density(SSTRd),lesion-to-liver ratio(SUVratio),MTV and TLG of primary tumor(SUV41%threshold).Parameters prognostic capability was assessed using ROC,discriminant and Kaplan-Meier analyses.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Briganti V

Authors: Briganti V, Berti V, Abenavoli E, Linguanti F, Ciaccio A,

Keywords: typical lung carcinoid, FDG PET, SSTR imaging, MTV, TLG,