Introduction: Recent studies have proposed new molecular imaging tracers, such as 18F-DOPA and 68Ga-DOTANOC, for the detection of recurrent/residual neuroendocrine tumors (NET) in case of negative conventional imaging modalities.
Aim(s): To evaluate sensitivity of 18F-DOPA PET/CT and 68Ga-DOTANOC PET/CT in the detection of residual/recurrent NET.
Materials and methods: Fifteen patients with NET were enrolled. All had biochemical evidence of recurrent/residual disease, not evident at conventional imaging techniques. Six patients had medullary thyroid carcinoma (MTC) with post-surgical persistence of increased calcitonin, two had a suspicion of pheocromocytoma, five had SDHB and SDHD mutation gene underlying multiple/malignant polyglandular (PGL) syndrome and two had MEN-1. All patients underwent 18F-DOPA (13 cases) or 68Ga-DOTANOC PET/CT (two cases).
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: Imaging (radiology, nuclear medicine, endoscopy)
Presenting Author: Andrea Lania
, Filopanti M
, Fugazzola L
, Rodari M
, Lopci E
, Chiti A
, Schiavi F
, Lania A
, Opocher G
, Spada A
, Beck-Peccoz P
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