Introduction: In Multiple Endocrine Neoplasia type 1 (MEN-1) pituitary, parathyroid and pancreatic/duodenal endocrine cells are typically involved. Other neoplasms also occur.
Aim(s): To present the first case of a MEN-1 syndrome with mixed neuroendocrine breast cancer with adrenal metastases.
Materials and methods: A 56-year-old MEN-1 female patient with Zollinger-Ellison syndrome, who had already been treated with a subtotal paratiroidectomy and excision of a single abdominal nodal metastasis of gastrinoma, developed a 4.5 cm right adrenal mass. A 111-Indium-Octreoscan showed a focal uptake in the right breast. The patient underwent enucleation of the mammary lesion, right adrenalectomy and excision of a small (2.0 mm size) duodenal lesion.
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: Clinical cases/reports
Presenting Author: professor Claudio Pasquali
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