Assessment of the Growth Rate of Paragangliomas Related to SDHx Gene Mutations Using Computed Tomography. Abstract #1380

Introduction: SDHx mutations are associated with a lifelong risk of multifocal paragangliomas (PGL), so patients need regular follow-up examinations.
Aim(s): The aim of the study was to estimate the growth rate of PGL and analyze of its depending on the location base on computed tomography (CT) images.
Materials and methods: 27 patients with SDHx mutations (21 SDHD,6 SDHB,19 index case) who had at least two CT examinations were included to the study. We analyzed 58 PGL (23 abdominal, 1 pheochromocytoma, 9 thoracic, 25 head and neck). A mean percentage volume (in ml) increase within a month and the volume doubling time were estimated. The patients treated by radio-, chemio-, radionuclear therapy were excluded from the analysis. The PGL were divided depending on their localization into: head,neck (HN), thoracic (TH), abdomen,pelvis (AP).
Conference: 13th Annual ENETS conference 2016 (2016)
Category: Epidemiology/Natural history/Prognosis - Prognosis
Presenting Author: Ilona Michałowska

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