Atypical Bronchial Carcinoid: Different Therapeutical Approachs

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Introduction: Choosing an adequate treatment for atypical bronchial carcinoid can improve quality of life and survival.

Aim(s): We present 2 examples of different therapeutic decisions in metastatic disease.

Materials and methods: 74 years old patient was diagnosed with a right pulmonar nodule as well as ipsilateral hiliar lymphadenopathy, liver and disseminated bone metastases. Histology demostrated a Ki67:12%. Two years after diagnosis the patient underwent chemotherapy with Everolimus. Afterwards, Peptide Receptor Radionuclide Therapy (PRRT) with 90Yttrium-DOTATOC was started, achieving a disease stabilisation. Therapy control was performed with 68GaDOTATOC PET-CT showing no significant changes. An additional 18FFDG PET was negative. At present the patient is treated by octeotride therapy. 20 years old patient with atypical bronchial carcinoid in the left lung showed a Ki67:3%. Initially he underwent surgery with lobectomy and local lymphadenectomy. Two years later 68GaDOTATOC PET-CT controls demonstrated diseminated liver metastases. A stabilisation was finally achieved with octreotide.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Geraldo Roig L,

Keywords: 68GaDOTATOC PET-CT, neuroendocrine tumor, atypical bronchial carcinoid, octreotide, PRRT,