Bone Metastases in NEN Patients - Frequency, Clinical, Therapeutic and Prognostic Relevance

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Introduction: Up to 73% of patients with neuroendocrine neoplasms (NEN) present with distant metastases at diagnosis. Advanced stage negatively correlates with prognosis. Bone metastases (BM) are usually reported in less than 10% of patients. Improved imaging results in more frequent detection but information in general is very limited.

Aim(s): Presentation of a single-center experience on frequency, clinical and therapeutic relevance of BM.

Materials and methods: All patients treated in the ENETs center in Marburg, Germany, between 2000 and June 2015 listed in our NEN-database were evaluated for inclusion. Out of 709 patients 414 had distant metastases (58.4 %) including 109 with BM (15.4%). 84 patients qualified for inclusion in our study.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Scharf M, Michel V, Rinke A, Gress T,

Keywords: bone metastases, frequency, relevance,