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Chromogranin A as a Predictor of Progression, Regression or Stable Disease in Ileo-Cecal Neuroendocrine Tumors

#231

Introduction: Chromogranin A is an excellent marker for NET and tumor volume. Plasma CgA is suggested as the most reliable marker in follow-up of patients with some types of NET.

Aim(s): Changes in plasma CgA concentrations were compared to changes in CT according to the RECIST 1.1 criteria in a well-definded group of mid-gut NET.

Materials and methods: We investigated the diagnostic accuracy of plasma CgA as a predictor for progression, regression or stable disease compared to changes on CT scan using RECIST 1.1. in 84 patients with CgA positive midgut neuroendocrine tumors (NET), retrospectively, from file. CgA were measured with a radioimmunoassay specific for the hCgA(340-348) sequence.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Jensen K, Hilsted L, Jensen C, Mynster T, Knigge U,

Keywords: Chromogranin-A, carcinoid tumors, neuroendocrine tumors, computer tomography, RECIST 1.1,

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