Clinical and Morphological Features of Extrapulmonary Small-Cell Cancer

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Introduction: Extrapulmonary Small-cell cancer (ESCC) is an extremely rare disease. Usually in the treatment of patients with ESCC approaches to the treatment of patients with small cell lung cancer (SCLC) are used.

Aim(s): To reveal clinical and morphological features of patients with ESCC in comparison with patients with SCLC. To assess the frequency of expression of the receptors for somatostatin in patients with ESCC and SCLC.

Materials and methods: a set of two groups of patients was performed: group A of 36 patients with ESCC. All patients with ESCC have studied for expression of somatostatin receptors 2 and 5 types, levels of serotonin, chromogranin A and NSE in the serum. All patients in the first line of therapy received treatment with etoposide and platinum preparations. Group B of 52 patients with SCLC. All patients underwent the study of expression of somatostatin receptors 2 and 5 types. Patients received treatment on the basis of etoposide and platinum preparations in first line of chemotherapy.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Ivanov A, Gorbunova V, Delektorskaya V, Kuzminov A,

Keywords: small cell cancer, Extrapulmonary small cell cancer, somatostatin receptors,