Complete Remission of Hepatic Metastasis after Total Gastrectomy for a Gastric Carcinoid Tumor Type 1: A Case Report
#1741
Introduction: A 58-year-old woman was referred to our hospital for hepatic lesions and thickening of the walls of the stomach detected by abdominal CT scan. An upper GI endoscopy showed a lesion of the body of the stomach and the histopathologic exam documented a well differentiated NET. 68Ga-DOTATOC PET showed pathologic uptake in the stomach and in the liver (3 lesions). Circulating chromogranin A and gastrin were 596 ng/ml and 2283 pg/ml respectively
Aim(s):
Materials and methods: A total gastrectomy was performed with the aim to remove primary tumor and the source of hypergastrinemia. The intraoperative ultrasound of the liver documented 6 small liver metastasis. Final pathology report confirmed a diagnosis of well-differentiated NET G2 (WHO 2010), with a mitotic count 15/10 HPFs and Ki67 20%, stage pT3N1. Due to the negative immunostaining for gastrin and the presence of chronic atrophic gastritis, a diagnosis of a type I gastric carcinoid was made. Circulating gastrin normalized one month later
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Smiroldo V
Authors: Smiroldo V, Carnaghi C, Tresoldi A, Lania A, Bonifacio C,
Keywords: gastric, NET, complete remission, gastrin,
To read the full abstract, please log into your ENETS Member account.