Correlation Between the 18F-FDG Uptake and Pathological Data in Well-Differentiated Digestive and Pulmonary Neuroendocrine Tumors (NET)

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Introduction: The 18F-FDG uptake assessed by PET/CT is correlated to prognosis in most tumors.

Aim(s): The aim of our study was to compare the 18F-FDG uptake with tumor proliferation (Ki67) and expression of molecules related to cell metabolism [hypoxia (VHL), glucose transport (GLUT-1), cellular pH (CA9)] in well differentiated NET.

Materials and methods: This retrospective study included 22 patients. 18F-FDG uptake was assessed by the SUVmax value (Standardized Uptake Values). An immunohistochemical study was performed with Ki67, VHL, GLUT-1 and CA9 antibodies.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Bucau M, Laurent-Bellue A, Cros J, Hentic O, Rebours V,

Keywords: Neuroendocrine tumors, PET-scan, 18-FDG, Ki67, VHL, metabolism,

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