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Depression and Carcinoid Syndrome: Is There Any Relationship? A Cross-Sectional Study

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Introduction: The relationship between brain serotonin and depression is well-established. It is also widely accepted that serotonin hyperproduction in carcinoid syndrome does not cross the brain barrier. CNS serotonin is synthesised from tryptophan within serotonergic neurons and a deficiency of this precursor could be possible on carcinoid patients.

Aim(s): In this cross-sectional study we evaluated, whether the feelings of depression are associated with neuroendocrine symptomatology. In addition, whether self-report of quality of life is associated with feelings of depression.

Materials and methods: Forty-seven patients with carcinoid syndrome completed a survey via clinic involving: QoL questionnaires and the Beck’s Depression Inventory-II. All questionnaires were counterbalanced.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Garcia-Hernandez J, Mohmaduvesh M, Davies P, Quaglia E, Toumpanakis C,

Keywords: depression, carcinoid, quality of life, neuroendocrine,

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