Detection within a Neuroendocrine Tumor of High Levels of B-Lymphocyte Stimulator (BLyS) Correlates with a Greater Disease Severity

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Introduction: .

Aim(s): Potential prognostic role of cytokine B-Lymphocyte Stimulator (BLyS) in follow-up of NET patients.

Materials and methods: 124 unselected patients (disease duration 5.9±4.4 yrs) with NET: 36 lung NET, 47 gastrointestinal NET and 41 pancreatic lesions. In 23 cases BLyS was repeatedly assessed during follow-up, the disease was monitored according to RECIST criteria. Patients were compared with a group of 77 healthy blood donors, matched for age and sex. Serum levels of BLyS and CgA were analyzed using ELISA.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Grimaldi F, Motta C, Cipri C, Tonelli V, Pistis C,

Keywords: Tumor marker,