Diagnosis and Management of Thymic Neuroendocrine Tumors: A Case Series Review

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Introduction: Thymic neuroendocrine tumors (TNET) represent rare types of thymic tumors with an incidence of 0.01/100000 per year. They commonly show rapid disease progression and are rarely curable.

Aim(s): To review retrospectively all cases of TNETs treated in our Unit, focusing on initial presentation, treatment and survival.

Materials and methods: Seven cases (five female, two male) with full follow-up were included. Mean age at diagnosis was 52.4 (range 33-66). Histology was available in six patients. Five met the WHO histological criteria for TNET, and one thymic carcinoma with neuroendocrine features. All patients underwent CT, Octreoscan (or Ga-68octreotate PET) ±123 MIBG scan at diagnosis/follow-up

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Akay E, El-Khouly F, Khan M, Caplin M, Toumpanakis C,

Keywords: thymic, thymic neuroendocrine tumor, radical thymectomy, chemotherapy, somatostatin analogues, Y-90,