Diffusion Weighted Imaging as a Screening Tool in the Detection and Monitoring of Pancreatic Neuroendocrine Tumours in Patients with Familial Cancer Syndromes.

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Introduction: Pancreatic neuroendocrine tumours (PNETs) occur at a higher frequency and at a younger age in patients with certain genetic conditions e.g. Von Hippel Lindau and Multiple Endocrine Neoplasia type 1. Screening for early detection and monitoring growth rates of PNETs in these high risk patients is vital in their management. MRI has emerged as the gold standard for imaging the pancreas for the detection of PNETs and diffusion weighted imaging (DWI) has become an invaluable adjunct.

Aim(s): We aim to further explore the value of DWI in initial characterisation and in monitoring the tumour growth rate in these high risk groups.

Materials and methods: Analysis of our tertiary referral centre identified 61 patients that had MRI pancreas during the last 10 years for indications including screening for VHL, MEN and the investigation of functional PNETs. These images were retrospectively reviewed.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Jenkins C, Thomas W, Parry C, Khan M, Owen R,

Keywords: PNET, MRI, VHL, MEN1,