Diverging Incidence and Survival Trends for Neuroendocrine Tumors due to Histological Grade

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Introduction: Epidemiological data of NET are mostly classified according to the primary site of the tumor. However, a pathologic classification, irrespective of primary site, might be more informative.

Aim(s): We evaluated the epidemiological and survival data of patients diagnosed with NET stratified by histological grade.

Materials and methods: 42,008 patients with NET were identified by the Netherlands Cancer Registry from 1990-2008. We defined four groups: well-differentiated NET, grade 1 and 2 (G1NET and G2NET), poorly differentiated large and small cell neuroendocrine carcinoma (G3LCC and G3SCC). The relative survival rates (RSR) were given at five years for 1990–1999 and for 2000–2008.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Korse C, Taal B, van Velthuysen M, Visser O,

Keywords: neuroendocrine tumors, epidemiology, survival, pathology, classification,