Efficacy and Safety of the Combination Streptozotocin, 5-FU in Endocrine Pancreatic Tumors: A Retrospective Study

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Introduction: The combination of Streptozotocin with 5-FU has been used during the past decades in our institution as the first-line treatment in pancreatic NETs with low to moderate proliferation.

Aim(s): To assess the safety and efficacy of the combination of Streptozotocin and 5-FU.

Materials and methods: A retrospective study has been performed, using the medical records of 146 patients with endocrine pancreatic tumors who received the combination treatment of streptozotocin and 5-FU during the period 1981-2010.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Antonodimitrakis P, Skogseid B, Hurtig M, Oberg K, Granberg D,

Keywords: Streptozotocin, 5-FU, endocrine pancreatic tumors, progression-free survival, side effects,