Efficacy of Lutetium-177 DOTA Octreotate Peptide Receptor Radionuclide Therapy in Patients with Advanced Neuroendocrine Tumours and Carcinoid Syndrome Refractory to Somatostatin Analogues Abstract #1363

Introduction: Somatostatin Analogues (SSAs) are considered the gold standard treatment in Neuroendocrine Tumours (NETs) and carcinoid syndrome.
Aim(s): To assess the effect of Peptide Receptor Radionuclide Therapy (PRRT) on refractory carcinoid syndrome.
Materials and methods: A retrospective analysis included 35 patients with advanced NETs and refractory carcinoid syndrome despite maximum doses of SSAs, who had Lutetium177 DOTA Octreotate PRRT. Pre- and post- PRRT assessment of flushing, bowel frequency and 24h urine 5-Hydroxyindoleacetic Acid (5-HIAA) was performed.
Conference: 13th Annual ENETS conference (2016)
Category: Medical treatment - Targeted therapies
Presenting Author: Dr Apostolos Koffas

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