Enhancing Diagnostic Precision Through Combined Genomic and Histopathological Analysis of Pancreatic Neuroendocrine Tumors Abstract #2272

Introduction: Diagnostic differentiation of uncommon pancreatic malignancies can be challenging, but is essential for accurate clinical management; genomic analysis may provide a tool for making this critical distinction.
Aim(s): To augment traditional pathology with multi-modal genomic analysis in order to improve diagnostic differentiation of rare pancreatic malignancies.
Materials and methods: Targeted DNA sequencing, RNA expression analysis and immunohistochemistry (IHC) alongside pathological examination were employed to search for molecular drivers in a study of 60 patients with pancreatic neuroendocrine tumours (pNETs), and incidentally provided valuable evidence for re-diagnosis.
Conference: 15th Annual ENETS conference (2018)
Category: Basic Science - Genetics, epigenetics, miRNAs, Omics
Presenting Author: Tamsin Robb

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