Epidemiology of NENs and miRNA-224/LDL-C Level as an Independent Risk Factor in Jiangsu People’s Hospital

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Introduction: Studies show an increasing incidence trend in the neuroendocrine neoplasms(NENs).However,diagnosis and treatment of NENs are still big challenges.It has not been realized that deficiency of serum low density lipoprotein cholesterol(LDL-C) is a risk factor of NENs.

Aim(s): To investigate incidence trends of NENs in Jiangsu People’s Hospital and uncover the role of LDL-C on NENs.

Materials and methods: The data of 164 patients with NENs were retrospectively analyzed. Human pancreatic NENs cell line BON-1 was used to explore the role of miR-224/LDL-C/glucocorticoid(GC) on NENs.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Bai j

Authors: Bai j, Tang q, Wei y, He n, Hu y,

Keywords: NEN, miR-224, LDL-C, survival,