Expression and Clinical Significance of Alpha-internexin in Gastroenteropancreatic Neuroendocrine Neoplasm Abstract #1440
Introduction: Alpha-internexin is a 66-kDa neuronal intermediate filament protein, data on its role in gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) are limited.
Aim(s): To explore the expression and the epigenetic regulation mechanism of α-internexin in GEP-NEN and investigate its clinical significance.
Materials and methods: α-internexin was detected by immunohistochemistry in 286 GEP-NEN specimens. The methylation of α-internexin promoter was evaluated by bisulfite genomic sequencing.
Conference: 13th Annual ENETS conference (2016)
Presenting Author: Chen Jie
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