High Grade (G3) Neuroendocrine Neoplasms Should Be Further Classified According to Morphological Differentiation Abstract #920

Introduction: Neuroendocrine neoplasms (NENs) with a Ki-67 >20% (Grade 3) are classified together as Neuroendocrine Carcinomas (NEC), and are usually considered as poorly differentiated. However Grade (G)3 NENs may be heterogeneous, with some demonstrating a well-differentiated cell morphology.
Aim(s): To compare well-differentiated tumors (G3 WD-NETs) to poorly differentiated carcinomas (G3 PD-NECs).
Materials and methods: All G3 NENs referred between 2008 and 2013 were identified from a histopathology database. Clinical data analysed included Ki-67, imaging, response to treatment and overall survival (OS).
Conference: 11th Annual ENETS Conference (2014)
Category: ...none of the below
Presenting Author: Dr Dalvinder Mandair
Keywords: Ki-67, g3 NENs

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