Hyperammonemic Encephalopathy in Neuroendocrine Tumor Resolved Through Liver Embolization: A Case Report

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Introduction: Gastroenteropancreatic neuroendocrine tumors are a rare cause of secondary hyperammonemic encephalopathy. Possible etiological mechanisms are global hepatic dysfunction secondary to tumor burden or microvascular portosystemic shunting in the liver metastases often present in GEP-NET.

Aim(s):

Materials and methods: A 61-year-old women was diagnosed with a G1 pancreatic NET with diffuse liver metastases. Five months after diagnosis, under treatment with octreotide, the patient presented with confusion, ataxia, apraxia, inversion of circadian rhythm and incontinence.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Vandamme T, Kunnen J, Simoens M,

Keywords: embolization, hepatic encephalopathy,