Ileal GEP-NEN in Mother and Son – Option for Familial Disease Abstract #398

Introduction: Familial cases of ileal GEP-NEN have been described on some few occasions in the literature. Speculations of familial disease with or without a relationship to MEN-1 or other inherited endocrine neoplasias have been made
Aim(s): To describe a case of familial occurrence of ileal GEP-NEN in a woman and her son, both operated within a month at a single institution.
Materials and methods: We report on an 86-year-old woman operated for bowel obstruction with findings of a carcinoid primary tumor in the distal ileum, distal mesenteric lymph node metastases but no liver metastases. A wedge small bowel resection was performed and the recovery was uneventful. Four weeks later her 68-year-old son presented with abdominal pain and was found to have multiple liver metastases on ultrasound examination and a CT-scan showed a typical ileal GEP-NEN with mesenteric lymph node metastases and multiple small liver mets.
Conference: 9th Annual ENETS Conference (2012)
Category: Clinical
Presenting Author: MD, PhD Joakim Hennings

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